Blog: Tyrosine kinase inhibitors can have an effect on platelet function
Tyrosine kinase inhibitors (TKIs) are widely used as a targeted strategy for cancer treatment. However, due to their broad kinase target spectrum, most TKIs inevitably have off-target effects. Platelet function has been shown to be inhibited by TKIs, as they rely on the activity of several tyrosine kinases, including Tec, Btk, SFK, Lyn, Fyn, Syk. […]
