Quantifying secondary pharmacology antagonistic drug effects on platelet function
The development of new drugs is often limited or even halted by their side effects on platelet function. In drug discovery, identifying compounds that might have secondary pharmacological effects on platelet function can contribute to de-risking and help with the progression of potential new drugs. Half-maximal inhibitory concentration (IC50 or pIC50 (-log10IC50)), the concentration of […]
Platelet Services 2024 Round-up
From working on exciting client projects to attending industry events across the globe, it’s been another super busy but rewarding year here at Platelet Services HQ. In this end of year round-up, we discuss some of the highlights of our year and look ahead at what’s in store for us in 2025. Our technical […]
Intravenous antiplatelet therapy – for when the going gets tough
In the second instalment of our antiplatelet therapy series, we take a look at intravenous (IV) antiplatelet therapy and how it came to be used. In a previous blog1, we provided a brief overview of the 50-year evolution of oral anti-platelet therapy, which began with the findings of the first randomised, controlled trial of aspirin […]
American College of Toxicology (ACT) 44th Annual Meeting
The Platelet Services team will be attending and exhibiting at the ACT 44th Annual Meeting on the 12-15 November in Orlando, Florida, at the Rosen Shingle Creek Hotel. ACT brings together a community of scientists from pharmaceutical and biotech industries, regulatory agencies, CROs, academia, and R&D consultants. The highly anticipated Annual Meeting has a line-up […]
6th EUPLAN International Conference
Platelet Services will be attending the 6th EUPLAN International Conference, taking place at the University of Bristol on September 4-6 2023. EUPLAN 2023 is a prestigious event organised by the Platelet Society annually. The conference aims to provide a platform for researchers, clinicians, and industry experts to exchange knowledge, present cutting-edge research findings, and explore […]
BTS Discovery Toxicology 2023
Platelet Services will be attending BTS Discovery Toxicology 2023 “What’s new from small molecules to cell and gene therapies” on Wednesday 14th June at the Alderley Park Conference Centre. The one-day meeting will showcase strategies that are enabling more efficient and robust approaches to achieve success in drug discovery and development. Paul Cato, Senior Research Scientist, […]
WCP 2023 – 19th World Congress of Basic & Clinical Pharmacology
The Platelet Services team will be attending and exhibiting at the 19th World Congress of Basic & Clinical Pharmacology (WCP2023) on 2nd – 7th July at the Scottish Event Campus (SEC) in Glasgow, Scotland. The congress will bring together the global pharmacology and therapeutics community to discuss the latest cutting-edge science. The extensive programme includes […]
ELRIG Therapeutic OLIGO and European Chemical Biology Symposium 2023
Platelet Services will be attending the ELRIG meeting on Therapeutic OLIGOs combined with the 8th European Chemical Biology Symposium (ECBS) on May 9-11 at the AstraZeneca R&D site in Gothenburg. The three-day event will discuss the recent advancements in the discovery of therapeutic OLIGOs and in the Chemical Biology research field in Europe and across […]
Meet the team: Dr Paul Cato
Senior Research Scientist, Paul Cato, started out his career in haematology and shares the career journey that led him back to working with platelets here at Platelet Services. Always interested in science, Paul went to the University of the West of England (UWE) in Bristol to study biology. It was while he was studying towards […]
Andrew Johnson: Celebrating 40 years in science
Andrew Johnson is the Laboratory Manager at Platelet Services and this year, he celebrates 40 years working in science. In our latest blog, Andrew shares his career journey that led him to Platelet Services. From an early age, Andrew was always interested in science. At school he took CSEs but knew he needed to get […]
